Sixth Annual Charles H. Turner Young Investigator Bone Research Award Recipient
Kyung Shin Kang
Kyung Shin Kang (2016 recipient) received his Ph.D. in mechanical engineering from Pohang University of Science and Technology (POSTECH, South Korea) in 2013. He joined Dr. Alexander Robling’s lab in the Department of Anatomy and Cell Biology at Indiana University School of Medicine in order to develop his skills in mechanotransduction techniques. His long-term goal is to better understand anabolic effects of mechanical stimulation on bone remodeling. Also, he is interested in utilizing 3D culture models to study bone cell metabolism.
Title: Osteoclast-selective expression of Lrp5 HBM-causing mutations alters bone metabolism
By: Kyung Shin Kang and Alexander G Robling
Fifth Annual Charles H. Turner Young Investigator Bone Research Award Recipient
Erica L. Clinkenbeard
Erica L. Clinkenbeard (2015 recipient) received her Ph.D. degree from the University of Kentucky focusing on the porto-central gene regulation of hepatic alpha-fetoprotein by β-catenin as well as the role of hepatic zinc-finger homeobox 2 (Zhx2) in atherosclerosis incidence. Erica joined the lab of Dr. Ken White at Indiana University School of Medicine as a postdoctoral research fellow in 2012 where she is currently studying the regulation of fibroblast growth factor 23 (FGF23) in common and rare disorders of metabolic bone disease.
Title: Anemia and FGF23: identification of a novel mediator of phosphate metabolism
By: Erica L. Clinkenbeard, Keith R. Stayrook, Colin Ip, Taryn A. Cass, Lelia J. Summers, Mircea Ivan, Ernestina Schipani, Thomas L. Clemens, Kenneth E. White
Fourth Annual Charles H. Turner Young Investigator Bone Research Award Recipient
Perla C. Reyes Fernandez
Perla C. Reyes Fernandez (2014 recipient) graduated from the Autonoma University of Queretaro (Mexico) in 2006 with a BSc degree in Nutrition Science. She entered the Interdepartmental Nutrition PhD Program at Purdue University in 2010 where she joined Dr. James Fleet’s laboratory. Her PhD program has a Molecular and Biochemical Nutrition emphasis. Her dissertation is focused on identifying natural genetic variants that modulate the response of bone strength and structure to dietary calcium restriction.
Title: Duodenal Ca Absorption Increases to Compensate for the Loss of Vitamin D Receptor (VDR) from the Large Intestine and Kidney of Mice
By: Perla C. Reyes-Fernandez and James C. Fleet
Third Annual Charles H. Turner Young Investigator Bone Research Award Recipient
Pierre P. Eleniste
Pierre P. Eleniste (2013 recipient) received his Ph.D. degree from Northern Illinois University with a research emphasis on the production of stereoselective antibodies and their application as “tailor-made” chiral selectors in affinity techniques. In 2009, he joined Dr. Angela Bruzzaniti’s laboratory in the Department of Oral Biology at the Indiana University School of Dentistry. He performs research in the area of bone biology by identifying and characterizing key intracellular signaling proteins that are critical for osteoclast, osteoblast, and osteocyte activities.
Title: Novel Role for Dynamin Phosphorylation and GTPase Activity in Osteoblast Migration
By: Pierre P. Eleniste, Su Huang, and Angela Bruzzaniti
Second Annual Charles H. Turner Young Investigator Bone Research Award Recipient
Julia M. Hum
Julia Hum (2012 recipient) graduated from Saint Mary's College with a degree in Biology in 2007. She entered the Indiana University School of Medicine's BioMedical Gateway PhD program in 2008. Julia joined Dr. Fredrick Pavalko's laboratory in the Department of Cellular & Integrative Physiology in the summer of 2009. The primary goal of her PhD research was to investigate the molecular mechanisms underlying intergrin-mediated signaling that mediate bone's response to mechanical loading.
Title: Live Imaging of Src Activation in Osteocytes in Response to Mechanotransduction
By: Julia M. Hum, Suzanne R.L. Young, Richard N. Day, and Fredrick M. Pavalko
First Annual Charles H. Turner Young Investigator Bone Research Award Recipient
Sara Mantila Roosa
Sara Mantila Roosa (2011 recipient) received her BS in Biomedical Engineering from Michigan Technological University in 2004. She went on to pursue graduate studies in Biomedical Engineering at the University of Michigan. Her Master’s project was to investigate the effect of polycaprolactone scaffold pore size on bone regeneration and mechanical properties in an in vivo tissue engineering model. Sara received her MSE in Biomedical Engineering in 2006. After graduating from the University of Michigan, Sara joined Dr. Charles Turner’s lab at Indiana University Purdue University Indianapolis. The primary goal of her PhD research was to identify mechanical loading-induced gene expression patterns, and the governing regulatory mechanisms, that are most important in bone. She completed her PhD in Biomedical Engineering at Purdue University in 2010. At the time of the award, Sara was a postdoctoral research associate in the Center for Translational Musculoskeletal Research at Indiana University. She was working with her mentor, Dr. Stuart Warden, on a study investigating the lifelong skeletal benefits of exercise during growth by assessing bone health in former Major League Baseball players.
Title: Preliminary Evidence that Exercise During Growth Provides Lifelong Benefit to Bone Structure and Strength
By: Sara M. Mantila Roosa and Stuart J. Warden